It’s very confusing for medical students about which book to use for their PG entrance exams because these exams are based on multiple choice questions. So classic books are not enough for PG medical entrance exams preparation because MCQ books are based on exam pattern and it is good for quick revision. A student has limited time so these classic books are not helpful for them. There are some MCQ's which is commonly used in MCQ books with their answer.
Example of post-translational modification:
(A) Addition of selenocysteine
(B) Addition of alkyl group
(C) Conversion of arginine to citrulline
(D) All the above
Answer: All the above
The following are true, except:
(A) Glucokinase is present mainly in liver and pancreatic B cells.
(B) In liver under normal condition, hexokinase is saturated and supplies constantly glucose-6-phosphate.
(C) Hexokinase has high Km for glucose and is inhibited by glucose-6-phosphate.
(D) Glucokinase removes glucose from the blood following a meal and provides substrate for glycogen synthesis.
Answer: Hexokinase has high Km for glucose and is inhibited by glucose-6-phosphate.
Regarding glycogen phosphorylase, all are true, except:
(A) Glycogen phosphorylase catalyzes the rate limiting step of glycogenolysis.
(B) There are distinct isoenzymes of glycogen phosphorylase for liver and muscle.
(C) Glycogen phosphorylase requires pyridoxal phosphate as its co-enzyme.
(D) Deficiency of muscle phosphorylase leads to high blood lactate after exercise.
Answer: Deficiency of muscle phosphorylase leads to high blood lactate after exercise.
Co-enzymes for pyruvate dehydrogenase complex are all, except:
(A) TPP
(B) PLP
(C) Lipoic acid
(D) FAD
Answer: Answer: PLP
All of the following are true regarding regulation of pyruvate dehydrogenase (PDH) complex, except:
(A) PDH is inhibited by its products, i.e. acetyl CoA and NADH
(A) PDH is inhibited by its products, i.e. acetyl CoA and NADH
(B) Phosphorylation of the enzyme inactivates it.
(C) Kinase that phosphorylates PDH is activated by increase in [ATP]/ [ADP], [acetyl-CoA]/ [CoA] and [NADH]/ [NAD+].
(D) In adipose tissue where glucose provides acetyl-CoA for lipogenesis, the enzyme is inactivated in response to insulin.
Answer: In adipose tissue where glucose provides acetyl-CoA for lipogenesis, the enzyme is inactivated in response to insulin.
In methyl alcohol poisoning, ethyl alcohol is given as antidote. This leads to:
(A) Km decreases and Vmax increases.
(B) Km and Vmax remain constant.
(C) Km increases and Vmax decreases.
(D) Km increases and Vmax remains unchanged
Answer: Km increases and Vmax remains unchanged
